CODEXIS, INC.

Codexis, Inc.

Biotechnology • Healthcare • Redwood City, CA, United States • CDXS (NMS)

Codexis, Inc. provides enzymatic solutions for therapeutics manufacturing, leveraging its proprietary CodeEvolver technology platform to discover, develop, and enhance novel enzymes in the United States, Canada, Latin America, Europe, the Middle East, Africa, Australia, New Zealand, Southeast Asia, and China. The company develops its proprietary ECO Synthesis manufacturing platform to enable the scaled manufacture of RNAi therapeutics through an enzymatic route. It has a license agreement with Aldevron LLC and Pfizer Inc. The company was incorporated in 2002 and is headquartered in Redwood City, California.

650 421 8100 200 Penobscot Drive, Redwood City, CA 94063, United States

Stock Performance (90 Days)

Data through Dec 30, 2025
Layoff Events
Earnings Calls
Price updates on page refresh. Intraday quotes available during market hours (9:30 AM - 4:00 PM EST).

Layoff History

46 (5 sources) employees (24.0%) ✓ Verified
Nov 11, 2025
Codexis, Inc. implemented a workforce reduction of approximately 24% (46 positions) coinciding with a change in company leadership, with Dr. Alison Moore succeeding Dr. Stephen Dilly as CEO, effective November 7, 2025. This strategic overhaul, announced on November 6, 2025, aims to streamline operations, reduce operational expenses by recognizing an approximate $3.5 million expense in the fourth quarter of 2025, and extend the company's cash runway through 2027. The company is pivoting its strategic focus away from small molecule biocatalysis due to pricing pressures and towards innovative manufacturing solutions in its ECO Synthesis platform for oligonucleotide production. This includes reducing sales and marketing efforts in the small molecule biocatalysis segment. The workforce reduction is expected to be substantially completed by January 2026.
Small Molecule Biocatalysis (especially sales and marketing)Other departments not aligned with ECO Synthesis platform Redwood CityCA
Source: Companies that announced Major Layoffs and Hiring Freezes | Intellizence →

Earnings Call Transcripts

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Q4 2025 Neutral
Nov 6, 2025

CODEXIS, INC. announced a strategic pivot in Q4 2025, appointing Dr. Alison Moore as President and CEO and implementing a 24% workforce reduction. This restructuring, costing approximately $3.5 million, aims to streamline operations and intensify focus on its ECO Synthesis platform.

Recent News

Insider Sell: Will CDXS stock pay special dividends - 2025 Trading Volume Trends & Weekly Hot Stock Watchlists - moha.gov.vn
moha.gov.vn • Jan 1
Down 30% in 4 Weeks, Here's Why You Should You Buy the Dip in Codexis (CDXS) - Yahoo Finance
Yahoo Finance • Nov 11
Opaleye management sells Codexis (CDXS) shares worth $877,846 - Investing.com
Investing.com • Dec 15
Codexis Delivers Strong Q2 Results - Can The Stock Rebound? - RTTNews
RTTNews • Aug 14
Codexis Announces Workforce Reduction and New CEO - TipRanks
TipRanks • Nov 6

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Frequently Asked Questions

Has CODEXIS, INC. had layoffs?
Yes, CODEXIS, INC. has had 1 recorded layoff event, affecting a total of 46 employees. The most recent layoff was on November 11, 2025, impacting 46 employees.
How many employees does CODEXIS, INC. have?
CODEXIS, INC. has approximately 188 employees.
What industry is CODEXIS, INC. in?
CODEXIS, INC. operates in the Biotechnology industry, within the Healthcare sector.
Is CODEXIS, INC. a publicly traded company?
Yes, CODEXIS, INC. is publicly traded under the ticker symbol CDXS on the NMS. The company has a market capitalization of approximately $0.14 billion.
Where is CODEXIS, INC. headquartered?
CODEXIS, INC. is headquartered in Redwood City, CA, United States at 200 Penobscot Drive, Redwood City, CA 94063, United States.

Disclaimer

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